Ministry of Health, Labour and Welfare reported the number of demographic data in 2019. According to it, top 10 causes of death in 2019 are the below. This year Alzheimer's disease was ranked for the first time among the ten leading causes of death.
Table: Top 10 Causes of Death in Japan, 2019
| Rank | Cause | Cause | Cause | Number of deaths in 2019 |
| 1 | 悪性新生物 | Malignant neoplasm | Cancer | 376,425 |
| 2 | 心疾患 | Cardiac disease | Heart disease | 207,714 |
| 3 | 老衰 | Senility | Die of old age | 121,863 |
| 4 | 脳血管疾患 | Cerebrovascular disease | Brain vessel damage | 106,552 |
| 5 | 肺炎 | Pneumonia | Lung disease | 95,518 |
| 6 | 誤嚥性肺炎 | Aspiration pneumonitis | Aspiration | 40,385 |
| 7 | 不慮の事故 | Freak accident | Accident | 39,184 |
| 8 | 腎不全 | Renal failure | Kidney disease | 26,644 |
| 9 | 血管性等の認知症 | Vascular dementia | Dementia (vessel type) | 21,394 |
| 10 | アルツハイマー病 | Alzheimer's disease | Alzheimer | 20,730 |
| Others | Others | 324,684 | ||
| Total | Total | 1,381,093 |
Source is Ministry of Health, Labour and Welfare. 人口動態調査
www.mhlw.go.jp/toukei/saikin/hw/jinkou/kakutei19/index.html
www.mhlw.go.jp/toukei/saikin/hw/jinkou/kakutei19/xls/hyo.xls
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